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Romano Lab Selected Publications

Selected Publications

"Deep learning multi-omics integration identifies new molecular subtypes of lung cancer"
Gonda B., Wang D., Azim S.M., Romano G., Dehzangi I. 
BioData Mining. 2026 PMID: 42169010.

"Population analysis and immunologic landscape of melanoma in people living with HIV."
Barger L.N., Wang D., Saravia A., Mezzano V., Ward G., Loomis C., Feldman C., Tuluc M., Gaskill P.J.,  Seedor R., Coghill A.E., Suneja G., Dehzangi I., Hope J.L., Jour J., Romano G. 
Clinical Cancer Research. 2026; PMID: 41504629

"BAP1 loss affords lipotoxicity resistance in uveal melanoma"
Cunanan C.J., Amirfallah A., Sanders A.B., Gallant K.C., Cavallo M.R., Homer E.A., El-Naggar O.S., Farnan J.K., Romano G., Hope J.L., Jackson J.G., Hartsough E.J.
Pigment Cell and Melanoma Research. 2025; PMID: 40300851

"Disabling PSGL-1 abrogates immune suppression and resistance to PD-1 blockade in pancreatic cancer" 
Hope J.L., Zhang Y., Hetrick H.A.F., Sanchez-Hernandez E.S., Silvestri B., Smith B.J., Nakil S.H., Roy S., Lin M., Palete A.B., Maganti S., Ling L., Otero D.C., Byrne K., Romano G., Wang Y.X., Commisso C., Bradley L.M. bioRxiv [submitted to peer review]. 2025; PMID: 40501664

"Plasticity and functional heterogeneity of cancer-associated fibroblasts."
Flynn J.M., Thadani N., Gallagher E.E., Azzaro I., Bodnar C.M., McCarty C.P., Romano G., Webster M.R., Capparelli C.
Cancer Research. 2025; PMID: 40729489

"A structured curriculum supporting biomedical trainees' transition into independent academic positions and early career success."
Perez-Oquendo M., Romano G., Farris D.P., Gandhi V., Wistuba I.I., Tillman R.E., Udan R., Mangahas P., Soundararajan R.
BMC Medical Education. 2024; PMID: 38589919 

“Melanoma in people living with HIV: Immune landscape dynamics and the role of immuno- and antiviral therapies”
Barger LN, El Naggar OS, Ha B, Romano G
Cancer Metastasis Rev. 2024

“Microparticle-delivered Cxcl9 prolongs Braf inhibitor efficacy in melanoma”
Romano G, Paradiso F, Li P, Shukla P, Barger LN, El Naggar O, Miller JP, Liang RJ, Helms TL, Lazar AJ, Wargo JA, Taraballi F, Costello JCC, Kwong LN
Cancer Immunology Research. 2023

Additional publications...

"Tumor Microenvironment and Immune Escape in the Time Course of Glioblastoma"
Virtuoso A, De Luca C, Cirillo G, Riva M, Romano G, Bentivegna A, Lavitrano M, Papa M, Giovannoni R
Molecular Neurobiology. 2022

"Multi-modal molecular programs regulate melanoma cell state and clinical outcomes"
Andrews MC, Oba J, Zhu H, Wu C, Karpinets T, Creasy CA, Forget M, Yu Z, Song X, Mao X, Hoon DSB, Robertson AG, Romano G, Li P, Burton EM, Lu Y, Sloane RS, Wani KM, Rai K, Lazar AJ, Haydu LE, Bustos MA, Shen J, Chen Y, Patel KP, Morgan MB, Wargo JA, Kwong LN, Haymaker CL, Grimm EA, Hwu P, Zhang J, Gershenwald JE, Davies MA, Futreal PA, Bernatchez C, Woodman SE
Nature Communications. 2022

"BTK Inhibitors Synergise with 5-FU to Treat Drug-Resistant TP53-Null Colon Cancers"
Lavitrano, M., Ianzano, L., Bonomo, S., Cialdella, A., Cerrito, M. G., Pisano, F., Missaglia, C., Giovannoni, R., Romano, G., McLean, C. M., Voest, E. E., D'Amato, F., Noli, B., Ferri, G. L., Agostini, M., Pucciarelli, S., Helin, K., Leone, B. E., Canzonieri, V., and Grassilli, E.
J Pathol. 250:134-47.10.1002/path.5347 (2020)

"Specific Expression of a New Bruton Tyrosine Kinase Isoform (p65BTK) in the Glioblastoma Gemistocytic Histotype"
Sala, L., Cirillo, G., Riva, G., Romano, G., Giussani, C., Cialdella, A., Todisco, A., Virtuoso, A., Cerrito, M. G., Bentivegna, A., Grassilli, E., Ardizzoia, A., Bonoldi, E., Giovannoni, R., Papa, M., and Lavitrano, M.
Front Mol Neurosci. 12:2.10.3389/fnmol.2019.00002 (2019)

"miRNAs, Melanoma and Microenvironment: An Intricate Network"
Romano, G., and Kwong, L. N.
Int J Mol Sci. 18.10.3390/ijms18112354 (2017)

"The Path to Metastatic Mouse Models of Colorectal Cancer"
Romano, G., Chagani, S., and Kwong, L. N.
Oncogene. 37:2481-89.10.1038/s41388-018-0155-x (2018)

"BRAF Dimerization: An Underlying Resistance Mechanism in Low-Grade Pediatric Gliomas"
Romano, G., and Kwong, L. N.
Cancer Discov. 8:1064-65.10.1158/2159-8290.CD-18-0784 (2018)

"A Preexisting Rare PIK3CAE545K Subpopulation Confers Clinical Resistance to MEK Plus CDK4/6 Inhibition in NRAS Melanoma and Is Dependent on S6K1 Signaling"
Romano, G., Chen, P., Song, P., McQuade, J.L., Liang, R.J., Liu, M., Roh, W., Duose, D.Y., Carapeto, F.C. L., Li, J., Teh, J.L.F., Aplin, A.E., Chen,M., Zhang, J., Lazar, A.J., Davies, M.A., Futreal, P.A., Amaria, R.N., Zhang, D.Y., Wargo, J.A., and Kwong, L.N.
Cancer Discovery. 8:556-67.10.1158/2159-8290.Cd-17-0745 (2018)

"APOA-1Milano Muteins, Orally Delivered Via Genetically Modified Rice, Show Anti-Atherogenic and Anti-Inflammatory Properties in Vitro and in Apoe(-/-) Atherosclerotic Mice"
Romano, G., Reggi, S., Kutryb-Zajac, B., Facoetti, A., Chisci, E., Pettinato, M., Giuffre, M. R., Vecchio, F., Leoni, S., De Giorgi, M., Avezza, F., Cadamuro, M., Crippa, L., Leone, B. E., Lavitrano, M., Rivolta, I., Barisani, D., Smolenski, R. T., and Giovannoni, R.
Int J Cardiol. 271:233-39.10.1016/j.ijcard.2018.04.029 (2018)

"Thyrospheres from B-CPAP Cell Line with BRAF and TERT Promoter Mutations Have Different Functional and Molecular Features Than Parental Cells"
Caria, P., Pillai, R., Dettori, T., Frau, D. V., Zavattari, P., Riva, G., Romano, G., Pani, F., Bentivegna, A., Giovannoni, R., Pagni, F., Sogos, V., and Vanni, R.
J Cancer. 8:1629-39.10.7150/jca.18855 (2017)

"Resveratrol Impairs Glioma Stem Cells Proliferation and Motility by Modulating the Wnt Signaling Pathway"
Cilibrasi, C., Riva, G., Romano, G., Cadamuro, M., Bazzoni, R., Butta, V., Paoletta, L., Dalpra, L., Strazzabosco, M., Lavitrano, M., Giovannoni, R., and Bentivegna, A.
PLoS One. 12:e0169854.10.1371/journal.pone.0169854 (2017)

"The TGF-β Pathway Is Activated by 5-Fluorouracil Treatment in Drug Resistant Colorectal Carcinoma Cells"
Romano, G., Santi, L., Bianco, M. R., Giuffre, M. R., Pettinato, M., Bugarin, C., Garanzini, C., Savarese, L., Leoni, S., Cerrito, M. G., Leone, B. E., Gaipa, G., Grassilli, E., Papa, M., Lavitrano, M., and Giovannoni, R.
Oncotarget. 7:22077-91.10.18632/oncotarget.7895 (2016)

"A Functional Biological Network Centered on XRCC3: A New Possible Marker of Chemoradiotherapy Resistance in Rectal Cancer Patients"
Agostini, M., Zangrando, A., Pastrello, C., D'Angelo, E., Romano, G., Giovannoni, R., Giordan, M., Maretto, I., Bedin, C., Zanon, C., Digito, M., Esposito, G., Mescoli, C., Lavitrano, M., Rizzolio, F., Jurisica, I., Giordano, A., Pucciarelli, S., and Nitti, D.
Cancer Biol Ther. 16:1160-71.10.1080/15384047.2015.1046652 (2015)

"Inhibition of GSK3B Bypass Drug Resistance of p53-Null Colon Carcinomas by Enabling Necroptosis in Response to Chemotherapy"
Grassilli, E., Narloch, R., Federzoni, E., Ianzano, L., Pisano, F., Giovannoni, R., Romano, G., Masiero, L., Leone, B. E., Bonin, S., Donada, M., Stanta, G., Helin, K., and Lavitrano, M.
Clin Cancer Res. 19:3820-31.10.1158/1078-0432.CCR-12-3289 (2013)